The purpose of this Manual of Operating Procedures (MOP) is to assist Cohort Research Unit (CRU) site Principal Investigators (PIs), Study Coordinators, and other study staff with an overview of the site initiation process and implementation procedures for the Common Protocol for Collecting Data and Specimens from Participants in the Regional Prospective Observational Research for Tuberculosis (RePORT) Consortium (RePORT International Common Protocol). All study procedures must be conducted in accordance with the Common Protocol and this MOP. In the event that the MOP is not consistent with the protocol, the protocol specifications take precedence.

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