RePORT Philippines (Regional Prospective Observational Research for Tuberculosis) is a multi-organizational, collaborative effort that was initiated by the Philippine Council for Health Research and Development (PCHRD) of the Department of Science and Technology (DOST) in August 2017 through a Memorandum of Understanding with the National Institute of Allergy and Infectious Diseases (NIAID) of the US National Institutes of Health (NIH). The aim of the establishment of the consortium was to serve as foundation for national and international collaborations to facilitate communication in the collection, dissemination and sharing of information and knowledge on tuberculosis. This ties in with the role of PCHRD to promote discovery, development and marketing of novel drugs, diagnostic tests, vaccines, and other health technologies to foster a healthier and more productive nation. Funding and management of the consortium is provided by the Philippine Department of Science and Technology (DOST) and its agency, the Philippine Council for Health Research and Development (PCHRD).

 

RePORT Philippines has two sites- the University of the Philippines Manila- National Institutes of Health (UPM- NIH) and the De La Salle Medical and Health Sciences Institute (DLSMHSI). Both sites have their own individual parent protocols which incorporate the RePORT common protocol. UPM-NIH has started study enrolment in June 2018 while DLSMHSI is currently in preparations for the start of their study.

The following are the sites of RePORT Philippines and a brief description of their studies.

Project Name Project Aims, Partnerships and Timeline Principal Investigators (Consortium PIs)
Long-term Outcomes of Diagnosed Tuberculosis Cases in the Philippines

The study aims to determine the long-term outcomes of diagnosed TB cases in two communities near the capital of the Philippines. The Philippines RePORT study site is in the municipality of Los Baños in the province of Laguna in the Philippines. Recruitment is conducted in the public health clinics which cover a population of about 112,000 people (2015 census).

The UPM-NIH site has started enrollment of patients with active pulmonary TB (Cohort A) on June 21, 2018 and of household contacts of TB patients for Cohort B last August 22, 2018.

The project is expected to be funded for four years.

Anna Lena Lopez, MD, MPH

Community Approach to Control and Halt Drug Resistant TB (CoACH DRTB) The study aims to move the treatment of multidrug resistant TB patients closer to the community where they live in, using trained community TB health workers to improve adherence to the MDR TB Regimen. This site is currently setting up their study sites and their laboratory. Enrolment started in March 2019. Charles Y. Yu, MD